Ontology highlight
ABSTRACT:
ORGANISM(S): Gallus gallus
SUBMITTER: JAE HAN
PROVIDER: E-GEOD-22592 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
PloS one 20100923 9
<h4>Background</h4>Long-term maintenance of avian primordial germ cells (PGCs) in vitro has tremendous potential because it can be used to deepen our understanding of the biology of PGCs. A transgenic bioreactor based on the unique migration of PGCs toward the recipients' sex cord via the bloodstream and thereby creating a germline chimeric bird has many potential applications. However, the growth factors and the signaling pathway essential for inducing proliferation of chicken PGCs are unknown. ...[more]