Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling of S. cerevisiae histone H4 wild type and K91A mutant strain cultures

ABSTRACT: Yeast strain containing either a histone H4 wild type or K91A allele was grown in YPD to mid-log phase and harvested. Three replicates of each allele were performed

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Mark Parthun

PROVIDER: E-GEOD-2349 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Publications

Histone H4 lysine 91 acetylation a core domain modification associated with chromatin assembly.

Ye Jianxin J Ai Xi X Eugeni Ericka E EE Zhang Liwen L Carpenter Laura Rocco LR Jelinek Mary A MA Freitas Michael A MA Parthun Mark R MR

Molecular cell 20050401 1

The acetylation of the NH2-terminal tail of histone H4 by type B histone acetyltransferases (HATs) is involved in the process of chromatin assembly. Histone H4 associated with a nuclear type B HAT complex contains modifications in its globular core domain as well. In particular, acetylation was found at lysine 91. A mutation that alters this residue, which lies in the interface between histone H3/H4 tetramers and H2A/H2B dimers, confers phenotypes consistent with defects in chromatin assembly su ...[more]

PMID: 15808514

Similar Datasets

Yeast Histone H4 K91A versus wild type

Project description:Yeast strain containing either a histone H4 wild type or K91A allele was grown in YPD to mid-log phase and harvested. Three replicates of each allele were performed Keywords: repeat sample

2005-05-24 | GSE2349 | GEO

Histone H4 N-terminal tail mutants

Project description:A series of yeast carrying K->R mutations in the histone H4 N-terminal tail were profiled by gene expression array in mid-log phase. Keywords: repeat sample

2005-03-05 | GSE2324 | GEO

Histone H4 N-terminal tail mutants

Project description:A series of yeast carrying K->R mutations in the histone H4 N-terminal tail were profiled by gene expression array in mid-log phase.

2010-06-10 | E-GEOD-2324 | biostudies-arrayexpress

Transcription profiling of S. cerevisiae RPD3 deletion mutants and histone H3 and H4 amino-terminus mutants

2007-07-09 | E-GEOD-1639 | biostudies-arrayexpress

Rpd3 and histone H3 and H4 deletions/mutations

Project description:Signal intensity data for rpd3 delete, H3delta(1-28), H3(K4,9,14,18,23,27Q), H4delta(2-26), H4(K5,8,12,16Q), rpd3 delete H3delta(1-28), and rpd3 delete H4(K5,8,12,16Q) yeast grown in rich (YPD) media Keywords = histones Keywords = chromatin Keywords = rpd3 Keywords = HDAC Keywords = histone deacetylase Keywords = yeast Keywords: other

2004-09-04 | GSE1639 | GEO

Comparison of yeast (Saccharomyces cerevisiae) strain with histone H4 R45 mutated to H with wild type yeast strain WY139

Project description:Total RNA samples from three replicate cultures of wild type and mutant yeast strains was isolated and expression profile done using Affymetrix arrays. Comparsion between the samples indicate how mutation in a single amino acid residue in histone H4 (H4R45H) affects gene expression in yeast. Such a mutation in histone H4 is known to generate a specific class of mutants called SWI/SNF independent (SIN) mutants, and the mutants were identified by their ability to carry out transcription in the absence of yeast chromatin remodeling complex SWI/SNF. SIN mutations are known to affect higher order chromatin structure and the comparative expression profile would help identification of genes which get affected by such altered chromatin landscape. Keywords: mutant analysis

2008-06-23 | GSE11282 | GEO

Transcription profiling of S. cerevisiae strain with histone H4 R45 mutated to H with wild type yeast strain WY139

2008-10-20 | E-GEOD-11282 | biostudies-arrayexpress

Cryptococcus neoformans wild type and sir2delta

Project description:Wild type strain H99 compared to independent sir2 deletion mutants grown to mid-log (0.6 OD600) in rich medium (YPD) shaking at 250rpm in baffled flasks.

2022-04-01 | GSE173209 | GEO

Transcription profiling of S. cerevisiae wild type and amino-terminal mutant histone H3 and H4 strains

Project description:Yeast lacking the H3 or H4 amino termini, and corresponding wild type strains, were grown in synthetic media. These conditions induce Gcn4-activated transcription. Experiment Overall Design: Three replicates of the H4del(2-26) and corresponding wild type strains, and four replicates of the H3del(1-28) and corresponding wild type strains, were performed. Note the strains are congenic, but differ in whether the histones were present on TRP1 marked (H4) or LEU2 marked (H3) plasmids. Samples were analysed using Affymetrix S98 microarrays.

2007-09-21 | E-GEOD-4135 | biostudies-arrayexpress

Sef1-dependent gene expression in Saccharomyces cerevisiae

Project description:To understand the gene expression in Saccharomyces cerevisiae under fermentative and respiraotry conditions, we perfomred the genome-wide gene expression profiling for the log-phase cells of S. cerevisiae wild type, sef1 deletion, and hyperactive SEF1-VP16 mutants under the YPD and YPGly conditions.

2024-03-25 | GSE262043 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data