Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Jian-Liang Li
PROVIDER: E-GEOD-24346 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Lin Shuibin S Shen Huangxuan H Li Jian-Liang JL Tang Shaojun S Gu Yumei Y Chen Zirong Z Hu Chengbin C Rice Judd C JC Lu Jianrong J Wu Lizi L
The Journal of biological chemistry 20130124 9
SFMBT1 belongs to the malignant brain tumor domain-containing chromatin reader family that recognizes repressive histone marks and represses transcription. The biological functions and molecular basis underlying SFMBT1-mediated transcriptional repression are poorly elucidated. Here, our proteomic analysis revealed that SFMBT1 is associated with multiple transcriptional corepressor complexes, including CtBP/LSD1/HDAC complexes, polycomb repressive complexes, and malignant brain tumor family prote ...[more]