Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Illumina and Affymetrix SNP-array data for 2 ETV6/RUNX1-positive Acute Lymphoblastic Leukemia samples and corresponding normal samples


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE25102: Illumina SNP-array data for 2 ETV6/RUNX1-positive Acute Lymphoblastic Leukemia samples and corresponding normal samples GSE25116: Affymetrix SNP-array data for 2 ETV6/RUNX1-positive Acute Lymphoblastic Leukemia samples and corresponding normal samples Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Henrik Lilljebjörn 

PROVIDER: E-GEOD-25117 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Whole-exome sequencing of pediatric acute lymphoblastic leukemia.

Lilljebjörn H H   Rissler M M   Lassen C C   Heldrup J J   Behrendtz M M   Mitelman F F   Johansson B B   Fioretos T T  

Leukemia 20111118 7


Acute lymphoblastic leukemia (ALL), the most common malignant disorder in childhood, is typically associated with numerical chromosomal aberrations, fusion genes or small focal deletions, thought to represent important pathogenetic events in the development of the leukemia. Mutations, such as single nucleotide changes, have also been reported in childhood ALL, but these have only been studied by sequencing a small number of candidate genes. Herein, we report the first unbiased sequencing of the  ...[more]

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