Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Henrik Lilljebjörn
PROVIDER: E-GEOD-25117 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Lilljebjörn H H Rissler M M Lassen C C Heldrup J J Behrendtz M M Mitelman F F Johansson B B Fioretos T T
Leukemia 20111118 7
Acute lymphoblastic leukemia (ALL), the most common malignant disorder in childhood, is typically associated with numerical chromosomal aberrations, fusion genes or small focal deletions, thought to represent important pathogenetic events in the development of the leukemia. Mutations, such as single nucleotide changes, have also been reported in childhood ALL, but these have only been studied by sequencing a small number of candidate genes. Herein, we report the first unbiased sequencing of the ...[more]