Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Brian Cox
PROVIDER: E-GEOD-2519 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Lickert Heiko H Cox Brian B Wehrle Christian C Taketo Makoto M MM Kemler Rolf R Rossant Janet J
Development (Cambridge, England) 20050427 11
Differential gene regulation integrated in time and space drives developmental programs during embryogenesis. To understand how the program of gastrulation is regulated by Wnt/beta-catenin signaling, we have used genome-wide expression profiling of conditional beta-catenin mutant embryos. Known Wnt/beta-catenin target genes, known components of other signaling pathways, as well as a number of uncharacterized genes were downregulated in these mutants. To further narrow down the set of differentia ...[more]