Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling of mouse conditional knock out of beta-catenin by K19-CRE at E7.5


ABSTRACT: expression profile of conditional knock out of beta-catenin by K19-CRE at E7.5. Tested a wild type with two alleles of beta-catenin, a heterzyote with one deleted allele and the conditional null in the domain on cytokeratin 19 driven CRE expression

ORGANISM(S): Mus musculus

SUBMITTER: Brian Cox 

PROVIDER: E-GEOD-2519 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications

Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos.

Lickert Heiko H   Cox Brian B   Wehrle Christian C   Taketo Makoto M MM   Kemler Rolf R   Rossant Janet J  

Development (Cambridge, England) 20050427 11


Differential gene regulation integrated in time and space drives developmental programs during embryogenesis. To understand how the program of gastrulation is regulated by Wnt/beta-catenin signaling, we have used genome-wide expression profiling of conditional beta-catenin mutant embryos. Known Wnt/beta-catenin target genes, known components of other signaling pathways, as well as a number of uncharacterized genes were downregulated in these mutants. To further narrow down the set of differentia  ...[more]

Similar Datasets

2005-04-13 | GSE2519 | GEO
2015-11-04 | E-GEOD-47388 | biostudies-arrayexpress
2022-11-15 | PXD029435 | Pride
| PRJNA92057 | ENA
2018-12-31 | GSE50153 | GEO
2018-12-31 | GSE50152 | GEO
2009-02-10 | GSE14753 | GEO
2006-03-13 | E-TABM-81 | biostudies-arrayexpress
2007-04-04 | GSE7430 | GEO
2007-12-13 | E-GEOD-7430 | biostudies-arrayexpress