Unknown,Transcriptomics,Genomics,Proteomics

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Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE25886: Analysis of mRNA levels of GPCR and GPCR-related signaling proteins in 3 mouse cell lines: AtT20, BV2 and N18 GSE25894: Analysis of mRNA levels of GPCR and GPCR-related signaling proteins in the HEK293 cell line Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Jacqueline Lopez 

PROVIDER: E-GEOD-25901 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis.

Atwood Brady K BK   Lopez Jacqueline J   Wager-Miller James J   Mackie Ken K   Straiker Alex A  

BMC genomics 20110107


<h4>Background</h4>G protein coupled receptors (GPCRs) are one of the most widely studied gene superfamilies. Thousands of GPCR research studies have utilized heterologous expression systems such as human embryonic kidney cells (HEK293). Though often treated as 'blank slates', these cell lines nevertheless endogenously express GPCRs and related signaling proteins. The outcome of a given GPCR study can be profoundly influenced by this largely unknown complement of receptors and/or signaling prote  ...[more]

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