Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Jacqueline Lopez
PROVIDER: E-GEOD-25901 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Atwood Brady K BK Lopez Jacqueline J Wager-Miller James J Mackie Ken K Straiker Alex A
BMC genomics 20110107
<h4>Background</h4>G protein coupled receptors (GPCRs) are one of the most widely studied gene superfamilies. Thousands of GPCR research studies have utilized heterologous expression systems such as human embryonic kidney cells (HEK293). Though often treated as 'blank slates', these cell lines nevertheless endogenously express GPCRs and related signaling proteins. The outcome of a given GPCR study can be profoundly influenced by this largely unknown complement of receptors and/or signaling prote ...[more]