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Modulation of mRNA in human T-cell development (expression)

ABSTRACT: Gene expression of Double Positive, and Single Positive CD4+ human thymocytes We used microarrays to identify genes involved in T cell maturation

ORGANISM(S): Homo sapiens

SUBMITTER: Alberto Corradin

PROVIDER: E-GEOD-26156 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150.

Ghisi Margherita M Corradin Alberto A Basso Katia K Frasson Chiara C Serafin Valentina V Mukherjee Subhamoy S Mussolin Lara L Ruggero Katia K Bonanno Laura L Guffanti Alessandro A De Bellis Gianluca G Gerosa Gino G Stellin Giovanni G D'Agostino Donna M DM Basso Giuseppe G Bronte Vincenzo V Indraccolo Stefano S Amadori Alberto A Zanovello Paola P

Blood 20110506 26

Ontogenesis of T cells in the thymus is a complex process whose molecular control is poorly understood. The present study investigated microRNAs involved in human thymocyte differentiation by comparing the microRNA expression profiles of thymocytes at the double-positive, single-positive CD4(+) and single-positive CD8(+) maturation stages. Microarray analysis showed that each thymocyte population displays a distinct microRNA expression profile that reflects their developmental relationships. Mor ...[more]

PMID: 21551231

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Modulation of mRNA in human T-cell development

Project description:This SuperSeries is composed of the following subset Series: GSE26156: Modulation of mRNA in human T-cell development (expression) GSE26157: Modulation of mRNA in human T-cell development (miRNA) Refer to individual Series

2011-10-26 | E-GEOD-26158 | biostudies-arrayexpress

Modulation of mRNA in human T-cell development (miRNA)

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Expression data from CD4 single positive thymocyte subsets from C57BL/6 mice of 6-8 wks of age

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2012-02-13 | E-GEOD-30083 | biostudies-arrayexpress

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Gene Expression Profile of Medullary Epithelial Cells isolated from thymus of Bone Marrow (BM) reconstituted RAG1 null (control) and SCID NOD mouse

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2011-06-01 | E-GEOD-14209 | biostudies-arrayexpress

Expression data from human endoscopic biopsy samples

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2011-06-01 | E-GEOD-14208 | biostudies-arrayexpress

Expression array of peripheral neuro-ectodermal cell lines

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