Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Hume Stroud
PROVIDER: E-GEOD-27627 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Stroud Hume H Feng Suhua S Morey Kinney Shannon S Pradhan Sriharsa S Jacobsen Steven E SE
Genome biology 20110620 6
<h4>Background</h4>5-Hydroxymethylcytosine (5hmC) was recently found to be abundantly present in certain cell types, including embryonic stem cells. There is growing evidence that TET proteins, which convert 5-methylcytosine (5mC) to 5hmC, play important biological roles. To further understand the function of 5hmC, an analysis of the genome-wide localization of this mark is required.<h4>Results</h4>Here, we have generated a genome-wide map of 5hmC in human embryonic stem cells by hmeDIP-seq, in ...[more]