Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: M Esperanza Cerdan
PROVIDER: E-GEOD-30046 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Vizoso-Vázquez Angel A Lamas-Maceiras Mónica M Becerra Manuel M González-Siso M Isabel MI Rodríguez-Belmonte Esther E Cerdán M Esperanza ME
Applied microbiology and biotechnology 20111222 1
In Saccharomyces cerevisiae, adaptation to hypoxia/anaerobiosis requires the transcriptional induction or derepression of multiple genes organized in regulons controlled by specific transcriptional regulators. Ixr1p is a transcriptional regulatory factor that causes aerobic repression of several hypoxic genes (COX5B, TIR1, and HEM13) and also the activation of HEM13 during hypoxic growth. Analysis of the transcriptome of the wild-type strain BY4741 and its isogenic derivative Δixr1, grown in aer ...[more]