HIV Infection and Antiretroviral Therapy Have Divergent Effects on Mitochondria in Adipose Tissue
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ABSTRACT: Exploratory microarray analysis identified significant changes in gene expression in adipose tissue. These included changes in genes regulating lipid and steroid metabolic processes and electron carrier activity in HIV-infected patients receiving antiretroviral therapy (ART). Additional genes involved in metabolic processes and mitochondrial function were found to be up-regulated in the adipose tissue of HIV-positive patients compared with HIV-negative controls. To identify differential gene expression in different tissues (PBMC, muscle, adipose tissue) between HIV patient groups (HIV negative, HIV positive with ART, HIV positive without ART).
ORGANISM(S): Homo sapiens
SUBMITTER: Richard Lempicki
PROVIDER: E-GEOD-30310 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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