Transcriptomic analysis of CD4 T cells
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ABSTRACT: Treatment-naive HIV, HCV mono-/co-infected individuals with CD4+ T cell counts >300/uL were recruited, and the global gene expression profiles of CD4+ T cells were analyzed.Equal amount of CD4+ T cells isolated from each individual were pooled to form three replicative groups. Total RNA was isolated and analyzed by Affymetrix GeneChip Array. Differentially expressed genes were identified and further confirmed by qRT-PCR. To further understand the biological meanings underlying the transcriptome data the Gene Set Enrichment Analysis was used.
ORGANISM(S): Homo sapiens
DISEASE(S): HIV and HCV coinfected
SUBMITTER: lina yi
PROVIDER: E-MTAB-1014 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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