Dataset Information
Transcription profiling of rat rear leg muscle from normal and diabetic subjects treated with vanadyl sulfate
Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
DISEASE(S): normal
SUBMITTER: Gail Willsky
PROVIDER: E-GEOD-3068 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Utilization of two sample t-test statistics from redundant probe sets to evaluate different probe set algorithms in GeneChip studies.
BMC bioinformatics 20060110
<h4>Background</h4>The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with known concentration are often used to assess the relative performance of probe set algorithms. Given the fact that the spiked-in cRNAs do not represent endogenously expressed genes in experiments, it becomes increasingly important to have methods to study whether a particular probe set algorithm is more appropriate f ...[more]
