Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Distribution of Drosophila insulator proteins after ecdysone treatment in Kc cells


ABSTRACT: Here we examine changes in the distribution of Drosophila insulator proteins during the ecdysone response. We performed ChIP-seq analysis in Kc cells at 0, 3, and 48 hours of ecdysone treatment with antibodies against CP190, Su(Hw), dCTCF, and BEAF-32B. Examination of 4 different insulator proteins at 3 time points of ecdysone treatment.

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Ashley Wood 

PROVIDER: E-GEOD-30740 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications

Regulation of chromatin organization and inducible gene expression by a Drosophila insulator.

Wood Ashley M AM   Van Bortle Kevin K   Ramos Edward E   Takenaka Naomi N   Rohrbaugh Margaret M   Jones Brian C BC   Jones Keith C KC   Corces Victor G VG  

Molecular cell 20111001 1


Insulators are multiprotein-DNA complexes thought to affect gene expression by mediating inter- and intrachromosomal interactions. Drosophila insulators contain specific DNA-binding proteins plus common components, such as CP190, that facilitate these interactions. Here, we examine changes in the distribution of Drosophila insulator proteins during the heat-shock and ecdysone responses. We find that CP190 recruitment to insulator sites is the main regulatable step in controlling insulator functi  ...[more]

Similar Datasets

2011-10-13 | E-GEOD-30741 | biostudies-arrayexpress
2012-11-15 | E-GEOD-42086 | biostudies-arrayexpress
2013-09-15 | E-GEOD-41354 | biostudies-arrayexpress
2013-01-21 | E-GEOD-32584 | biostudies-arrayexpress
2015-02-24 | E-GEOD-62904 | biostudies-arrayexpress
2012-07-05 | E-GEOD-36735 | biostudies-arrayexpress
2012-03-29 | E-GEOD-36374 | biostudies-arrayexpress
2012-06-18 | E-GEOD-36393 | biostudies-arrayexpress
2012-06-18 | E-GEOD-37444 | biostudies-arrayexpress
2013-05-01 | E-GEOD-39664 | biostudies-arrayexpress