Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Yejun Tan
PROVIDER: E-GEOD-31222 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Tan Yejun Y Muise Eric S ES Dai Hongyue H Raubertas Richard R Wong Kenny K KK Thompson G Marie GM Wood Harold B HB Meinke Peter T PT Lum Pek Yee PY Thompson John R JR Berger Joel P JP
Molecular pharmacology 20120410 1
Selective peroxisome proliferator-activated receptor γ (PPARγ) modulators (SPPARγMs) have been actively pursued as the next generation of insulin-sensitizing antidiabetic drugs, because the currently marketed PPARγ full agonists, pioglitazone and rosiglitazone, have been reported to produce serious adverse effects among patients with type 2 diabetes mellitus. We conducted extensive transcriptome profiling studies to characterize and to contrast the activities of 70 SPPARγMs and seven PPARγ full ...[more]