Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: James Korkola
PROVIDER: E-GEOD-3218 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Korkola James E JE Houldsworth Jane J Chadalavada Rajendrakumar S V RS Olshen Adam B AB Dobrzynski Debbie D Reuter Victor E VE Bosl George J GJ Chaganti R S K RS
Cancer research 20060101 2
Adult male germ cell tumors (GCTs) comprise distinct groups: seminomas and nonseminomas, which include pluripotent embryonal carcinomas as well as other histologic subtypes exhibiting various stages of differentiation. Almost all GCTs show 12p gain, but the target genes have not been clearly defined. To identify 12p target genes, we examined Affymetrix (Santa Clara, CA) U133A+B microarray ( approximately 83% coverage of 12p genes) expression profiles of 17 seminomas, 84 nonseminoma GCTs, and 5 n ...[more]