Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of mouse oocytes in different development stages to study molecular events during oocyte development.


ABSTRACT: oocytes were collected from ovary by follicle stage. Targets from four biological replicates of each were generated and the expression profiles were determined using Affymetrix MOE430A and B. Experiment Overall Design: 4 biological replicates were analyzed

ORGANISM(S): Mus musculus

SUBMITTER: Hua Pan 

PROVIDER: E-GEOD-3351 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Transcript profiling during mouse oocyte development and the effect of gonadotropin priming and development in vitro.

Pan Hua H   O'brien Marilyn J MJ   Wigglesworth Karen K   Eppig John J JJ   Schultz Richard M RM  

Developmental biology 20051005 2


The molecular basis for acquisition of meiotic and developmental competence, the two main outcomes of oocyte development and essential for producing an egg capable of being fertilized and supporting development to term, is largely unknown. Using microarrays, we characterized global changes in gene expression in oocytes derived from primordial, primary, secondary, small antral, and large antral follicles and used Expression Analysis Systematic Explorer (EASE) to identify biological and molecular  ...[more]

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