Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Stephanie Huang
PROVIDER: E-GEOD-33531 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Huang S S Gulzar Z G ZG Salari K K Lapointe J J Brooks J D JD Pollack J R JR
Oncogene 20111219 37
Though prostate cancer is often indolent, it is nonetheless a leading cause of cancer death. Defining the underlying molecular genetic alterations may lead to new strategies for prevention or treatment. Towards this goal, we performed array-based comparative genomic hybridization (CGH) on 86 primary prostate tumors. Among the most frequent alterations not associated with a known cancer gene, we identified focal deletions within 5q21 in 15 out of 86 (17%) cases. By high-resolution tiling array CG ...[more]