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High-throughput sequencing of small RNAs from Brugia pahangi and Haemonchus contortus

ABSTRACT: Illumina sequencing of small RNAs from Brugia pahangi and Haemonchus contortus 4 samples examined, larval stage 3 and mixed sex adults from two parasitic nematode species.

ORGANISM(S): Brugia pahangi

SUBMITTER: Alan Winter

PROVIDER: E-GEOD-34539 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel.

Winter Alan D AD Weir William W Hunt Martin M Berriman Matthew M Gilleard John S JS Devaney Eileen E Britton Collette C

BMC genomics 20120104

<h4>Background</h4>MicroRNAs (miRNAs) play key roles in regulating post-transcriptional gene expression and are essential for development in the free-living nematode Caenorhabditis elegans and in higher organisms. Whether microRNAs are involved in regulating developmental programs of parasitic nematodes is currently unknown. Here we describe the the miRNA repertoire of two important parasitic nematodes as an essential first step in addressing this question.<h4>Results</h4>The small RNAs from lar ...[more]

PMID: 22216965

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