Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Chromatin immunoprecipitation of human erythroleukemia cell line K-562 with H3K4me2, H3K4me3, H3ac, H4ac, Histone H2B and Histone H3 antibodies using an ENCODE array


ABSTRACT: ENCODE ChIP-chip study using human myelogenous leukemia cell line K-562 and anti histone H3K4me2 (Abcam; ab7766); H3K4me3 (Abcam; ab8580); H3ac (Upstate; 06-599); H4ac (Upstate; 06-866); Histone H2B (Abcam: ab1790) and Histone H3 (Abcam: ab1791) antibodies. Each antibody experiment was conducted in three biological replicates, with two technical replicates performed for each biological replicate

ORGANISM(S): Homo sapiens

SUBMITTER: Shane Dillon 

PROVIDER: E-TABM-140 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications


We generated high-resolution maps of histone H3 lysine 9/14 acetylation (H3ac), histone H4 lysine 5/8/12/16 acetylation (H4ac), and histone H3 at lysine 4 mono-, di-, and trimethylation (H3K4me1, H3K4me2, H3K4me3, respectively) across the ENCODE regions. Studying each modification in five human cell lines including the ENCODE Consortium common cell lines GM06990 (lymphoblastoid) and HeLa-S3, as well as K562, HFL-1, and MOLT4, we identified clear patterns of histone modification profiles with res  ...[more]

Similar Datasets

2006-08-30 | E-TABM-138 | biostudies-arrayexpress
2010-12-03 | E-MTAB-336 | biostudies-arrayexpress
2010-12-29 | E-MTAB-334 | biostudies-arrayexpress
2009-03-31 | E-TABM-660 | biostudies-arrayexpress
2005-06-13 | E-MEXP-269 | biostudies-arrayexpress
2006-10-23 | E-TABM-114 | biostudies-arrayexpress
2008-04-16 | E-MEXP-1565 | biostudies-arrayexpress
2008-04-16 | E-MEXP-1563 | biostudies-arrayexpress
2004-05-07 | E-FLYC-4 | biostudies-arrayexpress
2004-05-07 | E-FLYC-2 | biostudies-arrayexpress