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Epigenetic profiling of WT and Ezh2-null MLL-AF9 murine leukemic cells

ABSTRACT: Chromatin immunoprecipitation (ChIP) for H3K27me3 followed by Solexa sequencing in WT and Ezh2-null leukemic cells from primary and secondary recipients. Leukemic cells from primary and secondary recipients of MLL-AF9-transduced WT and Ezh2-null cells were sorted for GFP and YFP expression and analyzed by Chip-Seq.

ORGANISM(S): Mus musculus

SUBMITTER: Amit Sinha

PROVIDER: E-GEOD-34962 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The Polycomb Repressive Complex 2 Is Required For MLL-AF9 Leukemia

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Expression profiling of secondary wild type (WT) and Ezh2-null murine MLL-AF9 AML

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Project description:Epigenetic profiling of WT and Ezh2-null MLL-AF9 murine leukemic cells

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ChipSeq of MLL1 in mouse leukemic blast cells

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