Unknown,Transcriptomics,Genomics,Proteomics

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Methylome analysis of nerd1-1 mutant seedlings


ABSTRACT: DNA methylation profiling in nerd1-1 mutant seedlings 2 biological replicates in dye-swap - MeDIP-chip

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: FranM-CM-'ois ROUDIER 

PROVIDER: E-GEOD-35344 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


In Arabidopsis, transcriptional gene silencing (TGS) can be triggered by 24 nt small-interfering RNAs (siRNAs) through the RNA-directed DNA methylation (RdDM) pathway. By functional analysis of NERD, a GW repeat- and PHD finger-containing protein, we demonstrate that Arabidopsis harbors a second siRNA-dependent DNA methylation pathway targeting a subset of nonconserved genomic loci. The activity of the NERD-dependent pathway differs from RdDM by the fact that it relies both on silencing-related  ...[more]

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