Gene expression analysis of developing limbs
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ABSTRACT: To evaluate geneexpression profile in developing joints vs adjacent growth plate in control and TGF-beta type II receptor conditional knock-out in limb mesenchyjme We obtained E14.5 autopods from two normal controls and two Tgfbr2Prx1KO littermate embryos. Samples were frozen in OTC and cryosectioned and subjected to laser-capture microdissection for RNA sampling for interzone, growth plate chondrocytes and interdigital tissue. RNas were subjected to microarray analysis
ORGANISM(S): Mus musculus
SUBMITTER: Anna Spagnoli
PROVIDER: E-GEOD-37287 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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