Analysis of gene expression change by gefitinib treatment in gefitinib sensitive PC9 and resistant PC9.
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ABSTRACT: We established a gefitinib-resistant cell line (PC-9GR), by serial exposure of gefitinib to PC-9, an originally gefitinib-sensitive lung cancer cell line (PC-9na), for long period.We collected total RNA from both PC-9 and PC-9GR and examined mRNA expression profile, comprehensively. Gefitinib induced gene expression was measured in human lung cancer cell line was measured at 48 hours after exposure to 1uM Gefitinib.
ORGANISM(S): Homo sapiens
SUBMITTER: Junko Hamamoto
PROVIDER: E-GEOD-38302 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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