Unknown,Transcriptomics,Genomics,Proteomics

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GEP data from BCWM.1 cells treated with LNA antimiR-155 or scramble control


ABSTRACT: microRNA-155 acts as an oncogenic miRNA in B-cell lymphoproliferative disorders including Waldenstrom Macroglobulinemia (WM) and Chronic Lymphocytic Leukemia (CLL). we used an 8-mer LNA (locked nucleic acid) phosphorothioate oligonucleotide targeting the seed region of miR-155 to effectively antagonize in vitro tumor growth in WM. We performed gene expression profiling (GEP) analysis on BCWM.1 cells after treatment with LNA antimiR-155 or scramble control for 48 hours.

ORGANISM(S): Homo sapiens

SUBMITTER: Yong Zhang 

PROVIDER: E-GEOD-39189 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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