Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Jorja Henikoff
PROVIDER: E-GEOD-39331 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Zentner Gabriel E GE Tsukiyama Toshio T Henikoff Steven S
PLoS genetics 20130228 2
ATP-dependent nucleosome remodelers influence genetic processes by altering nucleosome occupancy, positioning, and composition. In vitro, Saccharomyces cerevisiae ISWI and CHD remodelers require ∼30-85 bp of extranucleosomal DNA to reposition nucleosomes, but linker DNA in S. cerevisiae averages <20 bp. To address this discrepancy between in vitro and in vivo observations, we have mapped the genomic distributions of the yeast Isw1, Isw2, and Chd1 remodelers at base-pair resolution on native chro ...[more]