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MiR-K12-9 expression and inhibition

ABSTRACT: Transcriptional profiling of BJAB cells expressing miR-K12-9 and BCBL cells treated with miR-K12-9 inhibitor. To identify host RNA targets of KSHV miRNAs, we took advantage of the observation that RNAs targeted by miRNAs often display small reductions in their steady-state levels, perhaps as a result of their impaired translation. Accordingly, we examined cellular transcript accumulation by array-based expression profiling under four sets of conditions in which KSHV miRNAs were expressed or inhibited. Cells transfected with negative control miRNA compared to miR-K12-9 or negative miRNA inhibitor compared to miR-K12-9 inhibitor.

ORGANISM(S): Homo sapiens

SUBMITTER: Joseph Ziegelbauer

PROVIDER: E-GEOD-40093 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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