Ontology highlight
ABSTRACT:
ORGANISM(S): Oxytricha trifallax
SUBMITTER: John Bracht
PROVIDER: E-GEOD-41060 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Genome biology 20121017 10
<h4>Background</h4>Cytosine methylation of DNA is conserved across eukaryotes and plays important functional roles regulating gene expression during differentiation and development in animals, plants and fungi. Hydroxymethylation was recently identified as another epigenetic modification marking genes important for pluripotency in embryonic stem cells.<h4>Results</h4>Here we describe de novo cytosine methylation and hydroxymethylation in the ciliate Oxytricha trifallax. These DNA modifications o ...[more]