Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Methylation profiling categorizes HIV-associated lymphomas in two distinctive groups

ABSTRACT: HIV-positive patients have a higher risk of non-Hodgkin's lymphoma with poor prognostic features. To characterize features of HIV-associated lymphoma, we compared the DNA methylation profiles of 803 cancer-related genes in between 9 HIV-associated and 12 non-HIV lymphoma samples by Illumina GoldenGate Methylation Cancer Panel I microarray. Bisulfite-converted DNA from the 42 samples (duplicate analysis of 21 samples) were analyzed to obtain the methylation profiles of cancer-associated genes by using Illumina GoldenGate Methylation Cancer Panel I microarray.

ORGANISM(S): Homo sapiens

SUBMITTER: Akihiro Matsunaga 

PROVIDER: E-GEOD-42626 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

<h4>Background</h4>HIV-positive patients have a 60-fold to 200-fold increased incidence of non-Hodgkin lymphomas, including Burkitt lymphoma, diffuse large B-cell lymphoma, and primary central nervous system lymphoma. HIV-associated lymphomas frequently have features such as extranodal involvement, decreased responses to standard chemotherapy, and high relapse rates, which indicate a poor prognosis. General pathological features do not clearly differentiate HIV-associated lymphomas from non-HIV  ...[more]

Similar Datasets

Methylation profiling Methylation profiling categorizes HIV-associated lymphomas in two distinctive groups
2014-01-30 | GSE42626 | GEO
Methylation profiling Methylation profiling classifies HIV-associated lymphoma
2014-01-30 | GSE42372 | GEO
Transcriptomics Methylation profiling classifies HIV-associated lymphoma
2014-01-30 | E-GEOD-42372 | biostudies-arrayexpress
Transcriptomics DNA methylation profiles in primary cutaneous melanoma are associated with clinically significant pathologic features
2015-06-15 | E-GEOD-54623 | biostudies-arrayexpress
Transcriptomics Methylation analysis of cancer and control samples.
2012-11-01 | E-GEOD-33614 | biostudies-arrayexpress
Methylation profiling Methylation analysis of cancer and control samples.
2012-11-01 | GSE33614 | GEO
Transcriptomics DNA methylation profiling of somatic tissues from normal and trisomic fetuses
2011-05-06 | E-GEOD-25283 | biostudies-arrayexpress
Genomics Homo sapiens
| PRJNA225479 | ENA
Transcriptomics Diagnostic and prognostic utility of a unique epigenetic prognostic PHYMA signature in prostate cancer
2014-03-13 | E-GEOD-39603 | biostudies-arrayexpress
Methylation profiling Diagnostic and prognostic utility of a unique epigenetic prognostic PHYMA signature in prostate cancer
2014-03-13 | GSE39603 | GEO