Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Yingjie Chen
PROVIDER: E-GEOD-430 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Chen YingJie Y Park Soon S Li Yunfang Y Missov Emil E Hou Mingxiao M Han Xinqiang X Hall Jennifer L JL Miller Leslie W LW Bache Robert J RJ
Physiological genomics 20030815 3
Chronic unloading of the failing heart with a left ventricular assist device (LVAD) can decrease cardiac mass and myocyte size and has the potential to improve contractile function. To study the effect of chronic ventricular unloading on myocardial gene expression, a microarray (U133A, Affymetrix) profiling gene expression was compared before and after LVAD support in seven patients with idiopathic dilated cardiomyopathy and end-stage heart failure. On average, 1,374 +/- 155 genes were reported ...[more]