Transcription profiling of mouse lung and skin from A/J, C57BL/6J and C3H/HeMs strains treated with gamma rays to identify radiation-induced gene expression.
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ABSTRACT: Gene expression profiling was used to identify genes that display radiation-induced transcriptional change over mouse strain and tissue differences. Experiment Overall Design: Inbred A/J, C57BL/6J and C3H/HeMs female mice were irradiated by gamma-rays as local irradiation in single doses to the thorax or hind leg. The animals were sacrificed at 1, 12 and 72 hours after irradiation. Non-irradiated mice served as the controls. The lungs and skin were dissected and used for expression analysis. Each sample including non-irradiated control was hybridized with global control that derived from mixture of commercially available total RNA from ten organs.
ORGANISM(S): Mus musculus
SUBMITTER: Shuhei Noda
PROVIDER: E-GEOD-4312 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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