Unknown,Transcriptomics,Genomics,Proteomics

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Whole genome bisulfite sequencing of MDCK cells, before and after TGFB-induced epithelial-mesenchymal transition


ABSTRACT: Whole genome bisulfite sequencing of MDCK cells, before and after TGFB-induced epithelial-mesenchymal transition Sequencing of bisulfite converted DNA from MDCK cells untreated, and after a 30 days treatment with TGF beta

ORGANISM(S): Canis lupus familiaris

SUBMITTER: Antonio Gómez 

PROVIDER: E-GEOD-43697 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


Epithelial-to-mesenchymal transition (EMT) is a plastic process in which fully differentiated epithelial cells are converted into poorly differentiated, migratory and invasive mesenchymal cells, and it has been related to the metastasis potential of tumors. This is a reversible process and cells can also eventually undergo mesenchymal-to-epithelial transition. The existence of a dynamic EMT process suggests the involvement of epigenetic shifts in the phenotype. Herein, we obtained the DNA methyl  ...[more]

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