Dataset Information
Gene expression profile in offspring born before vs. after maternal bariatric surgery
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Frederic Guenard
PROVIDER: E-GEOD-44407 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Differential methylation in glucoregulatory genes of offspring born before vs. after maternal gastrointestinal bypass surgery.
Proceedings of the National Academy of Sciences of the United States of America 20130528 28
Obesity and overnutrition during pregnancy affect fetal programming of adult disease. Children born after maternal bariatric gastrointestinal bypass surgery (AMS) are less obese and exhibit improved cardiometabolic risk profiles carried into adulthood compared with siblings born before maternal surgery (BMS). This study was designed to analyze the impact of maternal weight loss surgery on methylation levels of genes involved in cardiometabolic pathways in BMS and AMS offspring. Differential meth ...[more]
