Ontology highlight
ABSTRACT:
ORGANISM(S): Haemophilus ducreyi
SUBMITTER: Eric Hansen
PROVIDER: E-GEOD-44413 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Infection and immunity 20130826 11
Expression of the lspB-lspA2 operon encoding a virulence-related two-partner secretion system in Haemophilus ducreyi 35000HP is directly regulated by the CpxRA regulatory system (M. Labandeira-Rey, J. R. Mock, and E. J. Hansen, Infect. Immun. 77:3402-3411, 2009). In the present study, we show that this secretion system is also regulated by the small nucleoid-associated protein Fis. Inactivation of the H. ducreyi fis gene resulted in a reduction in expression of both the H. ducreyi LspB and LspA2 ...[more]