Unknown,Transcriptomics,Genomics,Proteomics

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Haemophilus ducreyi 35000HPhfq relative to 35000HP


ABSTRACT: The goal of this study was to compare the global trascription profile of a Haemophilus ducreyi hfq deletion mutant to that of the wild type parental strain. This study includes three biological replicates (paired samples of mutant and wild type strains), and all three were subjected to dye swap.

ORGANISM(S): Haemophilus ducreyi

SUBMITTER: Eric Hansen 

PROVIDER: E-GEOD-44535 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


<h4>Unlabelled</h4>To adapt to stresses encountered in stationary phase, Gram-negative bacteria utilize the alternative sigma factor RpoS. However, some species lack RpoS; thus, it is unclear how stationary-phase adaptation is regulated in these organisms. Here we defined the growth-phase-dependent transcriptomes of Haemophilus ducreyi, which lacks an RpoS homolog. Compared to mid-log-phase organisms, cells harvested from the stationary phase upregulated genes encoding several virulence determin  ...[more]

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