Unknown,Transcriptomics,Genomics,Proteomics

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Comparative characterization of microRNA profiles of different genotypes of Toxoplasma gondii


ABSTRACT: The present study characterized comparatively the miRNA profiles of three different genotypes of T. gondii, identified genotype-shared miRNAs and strain-specific miRNAs. Compared the miRNA expression profiles of five T. gondii strains

ORGANISM(S): Toxoplasma gondii

SUBMITTER: Min-jun Xu 

PROVIDER: E-GEOD-45007 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Comparative characterization of microRNA profiles of different genotypes of Toxoplasma gondii.

Xu M J MJ   Zhou D H DH   Huang S Y SY   Zhao F R FR   Nisbet A J AJ   Lin R Q RQ   Song H Q HQ   Zhu X Q XQ  

Parasitology 20130529 9


The present study compared the miRNA expression profiles of five Toxoplasma gondii strains, namely RH (Type I, ToxoDB10), TgXD (Type I, ToxoDB10), PRU (Type II, ToxoDB1), QHO (Type II, ToxoDB1) and TgC7 (ToxoDB9), by Solexa deep sequencing, bioinformatics analysis and real-time quantitative PCR. A total of 7, 15, 10, 12 and 10 miRNAs were found from RH, TgXD, PRU, QHO and TgC7 strains, respectively. Thirteen miRNAs were shared by three genotypes, with only one miRNA shared by all of the 5 strain  ...[more]

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