Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Sarah Labib
PROVIDER: E-GEOD-46998 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Søs Poulsen Sarah S Jacobsen Nicklas R NR Labib Sarah S Wu Dongmei D Husain Mainul M Williams Andrew A Bøgelund Jesper P JP Andersen Ole O Købler Carsten C Mølhave Kristian K Kyjovska Zdenka O ZO Saber Anne T AT Wallin Håkan H Yauk Carole L CL Yauk Carole L CL Vogel Ulla U Halappanavar Sabina S
PloS one 20131119 11
There is great interest in substituting animal work with in vitro experimentation in human health risk assessment; however, there are only few comparisons of in vitro and in vivo biological responses to engineered nanomaterials. We used high-content genomics tools to compare in vivo pulmonary responses of multiwalled carbon nanotubes (MWCNT) to those in vitro in cultured lung epithelial cells (FE1) at the global transcriptomic level. Primary size, surface area and other properties of MWCNT- XNRI ...[more]