Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Heather Wick
PROVIDER: E-GEOD-47394 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hui Lisa L Wick Heather C HC Moise Kenneth J KJ Johnson Anthony A Luks Francois F Haeri Sina S Johnson Kirby L KL Bianchi Diana W DW
Prenatal diagnosis 20130604 9
<h4>Objective</h4>The objective of this study was to understand the biological pathways involved in twin-twin transfusion syndrome (TTTS) by performing global gene expression analysis of amniotic fluid (AF) cell-free RNA.<h4>Methods</h4>A prospective whole transcriptome microarray study analyzing cell-free RNA in AF from TTTS recipient twins and singleton controls was carried out. Significantly differentially regulated genes in TTTS cases (N = 8) versus matched controls (N = 8) were identified a ...[more]