Ontology highlight
ABSTRACT:
ORGANISM(S): Brucella melitensis
SUBMITTER: Qingmin Wu
PROVIDER: E-GEOD-48165 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Liu Wenxiao W Dong Hao H Li Jing J Ou Qixing Q Lv Yujin Y Wang Xiaolei X Xiang Zuoshuang Z He Yongqun Y Wu Qingmin Q
Scientific reports 20150805
The response regulator OtpR is critical for the growth, morphology and virulence of Brucella melitensis. Compared to its wild type strain 16 M, B. melitensis 16 MΔotpR mutant has decreased tolerance to acid stress. To analyze the genes regulated by OtpR under acid stress, we performed RNA-seq whole transcriptome analysis of 16 MΔotpR and 16 M. In total, 501 differentially expressed genes were identified, including 390 down-regulated and 111 up-regulated genes. Among these genes, 209 were associa ...[more]