Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

94 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

H3K27me3 in mortal and immortal breast cells

ABSTRACT: H3K27me3 changes during immortalization of breast cells. The aim of the study was to determine whether differential epigentic state of TERT gene is involved in immortalization of breast cells. comparison of Pre-Stasis, Post-Selection, and immortal cells

ORGANISM(S): Homo sapiens

SUBMITTER: Lukas Vrba

PROVIDER: E-GEOD-48456 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Efficient immortalization of normal human mammary epithelial cells using two pathologically relevant agents does not require gross genomic alterations

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-07-03 | E-GEOD-48504 | biostudies-arrayexpress

Chromatin immunopreciptiation of human breast epithelial HME1 cell lines over-expressing wild type or mutant p53 to study acetylation of histone H4

Project description:acetylation of histone H4 was studied using ChIP on chip technique in breast epithelial HME1 cell lines overexpressing wt or mutant p53

2008-10-25 | E-MEXP-1494 | biostudies-arrayexpress

Chromatin immunopreciptiation of human breast epithelial HME1 cell lines over-expressing wild type or mutant p53 to study acetylation of histone H3

Project description:acetylation of histone H3 was studied using ChIP on chip technique in breast epithelial HME1 cell lines overexpressing wt or mutant p53

2008-10-25 | E-MEXP-1493 | biostudies-arrayexpress

Chromatin immunopreciptiation of human breast epithelial HME1 cell lines over-expressing wild type or mutant p53 to study p53 binding

Project description:p53 binding was studied using ChIP on chip technique in breast epithelial HME1 cell lines overexpressing wt or mutant p53

2008-10-25 | E-MEXP-1491 | biostudies-arrayexpress

Histone H3 acetylation of miRNA genes in HMEC and HMF

Project description:Normal cell type specific histone H3 acetylation of miRNA genes. HMEC and HMF represent two distinct differentiated cell type present in mammary gland each with a distinct phenotype, a distinct epigenotype as well as distinct miRNA expression pattern. The aim of the study was to determine how epigenetic modifications including histone H3 acetylation affect miRNA expression. Two cell types HMEC vs. HMF. Biological replicates: 3 pairs of HMEC-HMF of 3 distinct genotypes. Immunoprecipitation using anti-acetylated histone H3 antibody (06-599, Millipore).

2011-04-05 | E-GEOD-28375 | biostudies-arrayexpress

Histone H3 lysine 27 trimethylation of miRNA genes in HMEC and HMF

Project description:Normal cell type specific histone H3 lysine 27 trimethylation of miRNA genes. HMEC and HMF represent two distinct differentiated cell type present in mammary gland each with a distinct phenotype, a distinct epigenotype as well as distinct miRNA expression pattern. The aim of the study was to determine how epigenetic modifications including histone H3 lysine 27 trimethylation affect miRNA expression. Two cell types HMEC vs. HMF. Biological replicates: 3 pairs of HMEC-HMF of 3 distinct genotypes. Immunoprecipitation using anti-histone H3 trimethylated at lysine 27 (07-449, Millipore).

2011-04-05 | E-GEOD-28376 | biostudies-arrayexpress

Histone H3 lysine 4 trimethylation of miRNA genes in HMEC and HMF

Project description:Normal cell type specific histone H3 lysine 4 trimethylation of miRNA genes. HMEC and HMF represent two distinct differentiated cell type present in mammary gland each with a distinct phenotype, a distinct epigenotype as well as distinct miRNA expression pattern. The aim of the study was to determine how epigenetic modifications including histone H3 lysine 4 trimethylation affect miRNA expression. Two cell types HMEC vs. HMF. Biological replicates: 3 pairs of HMEC-HMF of 3 distinct genotypes. Immunoprecipitation using anti-histone H3 trimethylated at lysine 4 (05-745, Upstate).

2011-04-05 | E-GEOD-28377 | biostudies-arrayexpress

Histone H3 lysine 9 dimethylation of miRNA genes in HMEC and HMF

Project description:Normal cell type specific histone H3 lysine 9 dimethylation of miRNA genes. HMEC and HMF represent two distinct differentiated cell type present in mammary gland each with a distinct phenotype, a distinct epigenotype as well as distinct miRNA expression pattern. The aim of the study was to determine how epigenetic modifications including histone H3 lysine 9 dimethylation affect miRNA expression. Two cell types HMEC vs. HMF. Biological replicates: 3 pairs of HMEC-HMF of 3 distinct genotypes. Immunoprecipitation using anti-histone H3 dimethylated at lysine 9 (CS200587, Millipore).

2011-04-05 | E-GEOD-28378 | biostudies-arrayexpress

H3K4me3 in mortal and immortal breast cells

Project description:H3K4me3 changes during immortalization of breast cells. The aim of the study was to determine whether differential epigentic state of TERT gene is involved in immortalization of breast cells. comparison of Pre-Stasis, Post-Selection, and immortal cells

2013-07-03 | E-GEOD-48457 | biostudies-arrayexpress

miRNA genes in HMEC and HMF

Project description:This SuperSeries is composed of the following subset Series: GSE28374: DNA methylation of miRNA genes in HMEC and HMF GSE28375: Histone H3 acetylation of miRNA genes in HMEC and HMF GSE28376: Histone H3 lysine 27 trimethylation of miRNA genes in HMEC and HMF GSE28377: Histone H3 lysine 4 trimethylation of miRNA genes in HMEC and HMF GSE28378: Histone H3 lysine 9 dimethylation of miRNA genes in HMEC and HMF Refer to individual Series

2011-04-05 | E-GEOD-28380 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data