Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Sangbae Kim
PROVIDER: E-GEOD-50490 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Lee Keun-Wook KW Lee Sung Sook SS Kim Sang-Bae SB Sohn Bo Hwa BH Lee Hyun-Sung HS Jang Hee-Jin HJ Park Yun-Yong YY Kopetz Scott S Kim Sung Soo SS Oh Sang Cheul SC Lee Ju-Seog JS
Clinical cancer research : an official journal of the American Association for Cancer Research 20141111 2
<h4>Purpose</h4>Activation of YAP1, a novel oncogene in the Hippo pathway, has been observed in many cancers, including colorectal cancer. We investigated whether activation of YAP1 is significantly associated with prognosis or treatment outcomes in colorectal cancer.<h4>Experimental design</h4>A gene expression signature reflecting YAP1 activation was identified in colorectal cancer cells, and patients with colorectal cancer were stratified into two groups according to this signature: activated ...[more]