Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Charlie Kim
PROVIDER: E-GEOD-50542 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Fontana Mary F MF Baccarella Alyssa A Pancholi Nidhi N Pufall Miles A MA Herbert De'Broski R DR Kim Charles C CC
Journal of immunology (Baltimore, Md. : 1950) 20141203 1
Activated macrophages are crucial for restriction of microbial infection but may also promote inflammatory pathology in a wide range of both infectious and sterile conditions. The pathways that regulate macrophage activation are therefore of great interest. Recent studies in silico have putatively identified key transcription factors that may control macrophage activation, but experimental validation is lacking. In this study, we generated a macrophage regulatory network from publicly available ...[more]