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Tumors with neoadjuvant chemotherapy

ABSTRACT: Using whole genome mRNA expression profiling of primary human tumors and unsupervised hierarchical cluster analyses, 3 novel molecular subsets (basal, luminal and p53-like subsets) of muscle-invasive bladder cancer (MIBC) were identified. 23 MVAC treated samples were used for the validation of three MIBC subsets MVAC cohort consisted of 23 FFPE pretreatment tumors (TURs) from a Phase III clinical trial were used to validate 3 molecular subsets including basal, luminal and p53-like subsets We used Illumina cDNA-mediated Annealing, Selection, Extension, and Ligation (DASL) assay that is specifically designed for the gene expression of RNA that is extracted from FFPE.

ORGANISM(S): Homo sapiens

SUBMITTER: Woonyoung Choi

PROVIDER: E-GEOD-52219 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Tumors with neoadjuvant chemotherapy

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