Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Epigenome study of normal human epithelial tissues

ABSTRACT: Genome wide DNA methylation profiling of normal human epithelial tissues of breast colon lung and endometrial origin, WBC and sperm to identify breast-specific methylated gene promoter loci. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Breast tissues were pre-enriched for organoids and other epithelial tissues were carefully selected by the pathologist. Bisulphite converted DNA from the 23 samples were hybridised to the Illumina Infinium 27k Human Methylation Beadchip v1.2. Two arrays of 12 and samples each were run separately. Each array included a control of human sperm DNA treated with SssI CpG methylase and human sperm DNA not treated (one sample did not pass QC and was dicarded ) .

ORGANISM(S): Homo sapiens

SUBMITTER: Ella Evron 

PROVIDER: E-GEOD-54025 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml

Similar Datasets

Methylation profiling Epigenome study of normal human epithelial tissues
2014-01-14 | GSE54025 | GEO
Transcriptomics Epigenome analysis of breast tissue from women with and without breast cancer.
2012-02-20 | E-GEOD-32393 | biostudies-arrayexpress
Transcriptomics DNA methylation profiling of serum DNA samples of the UKCTOCS cohort
2014-06-03 | E-GEOD-58119 | biostudies-arrayexpress
Transcriptomics Epigenome analysis of primary breast cancer tumors and different types of recurrences.
2013-12-24 | E-GEOD-44870 | biostudies-arrayexpress
Methylation profiling DNA methylation profiling of serum DNA samples of the UKCTOCS cohort
2014-06-03 | GSE58119 | GEO
Methylation profiling DNA methylation profiling of whole blood DNA samples from BRCA1 wild-types without breast cancer and BRCA1 mutants with and without breast cancer (Prague Set 1)
2014-05-06 | GSE57285 | GEO
Transcriptomics DNA methylation profiling of whole blood DNA samples from BRCA1 wild-types without breast cancer and BRCA1 mutants with and without breast cancer (Prague Set 1)
2014-05-06 | E-GEOD-57285 | biostudies-arrayexpress
Methylation profiling Epigenome analysis of primary MCL
2015-12-31 | GSE45253 | GEO
Transcriptomics Epigenome analysis of irradiated and non-irradiated breast tumor tissue samples and normal controls
2014-03-26 | E-GEOD-50220 | biostudies-arrayexpress
Transcriptomics Epigenome analysis of primary MCL
2015-12-31 | E-GEOD-45253 | biostudies-arrayexpress