Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Expression data from skin biopsies in pateints with systemic sclerosis treated with anti-TGF-beta, fresolimumab


ABSTRACT: Systemic sclerosis is associated with skin fibrosis thought mediated by TGFb. This open label clinical trial examines the effect of TGFb inhibition on skin gene expression. Patients 1-9 received two doses 1 mg/kg dose of fresolimumab at baseline and 3 weeks; patients 10-19 received a single 5 mg/kg dose Patients with diffuse cutaneous systemic sclerosis within 2 years of first raynauds had skin biopsies before treatment and the 3-4 weeks, 7 weeks and 24 weeks after treatment with fresolimumab

ORGANISM(S): Homo sapiens

SUBMITTER: Robert Lafyatis 

PROVIDER: E-GEOD-55036 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2015-06-05 | GSE55036 | GEO
2018-09-13 | PXD009771 | Pride
2015-08-27 | E-GEOD-65405 | biostudies-arrayexpress
2015-06-22 | E-GEOD-65336 | biostudies-arrayexpress
2014-06-07 | E-GEOD-47751 | biostudies-arrayexpress
2015-06-12 | E-GEOD-62649 | biostudies-arrayexpress
2017-03-31 | E-MTAB-5563 | biostudies-arrayexpress
| PRJNA1110840 | ENA
| PRJNA490744 | ENA
2013-01-30 | E-MEXP-32 | biostudies-arrayexpress