Transcriptomics

Dataset Information

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Expression data from skin biopsies in pateints with systemic sclerosis treated with anti-TGF-beta, fresolimumab


ABSTRACT: Systemic sclerosis is associated with skin fibrosis thought mediated by TGFb. This open label clinical trial examines the effect of TGFb inhibition on skin gene expression. Patients 1-9 received two doses 1 mg/kg dose of fresolimumab at baseline and 3 weeks; patients 10-19 received a single 5 mg/kg dose

ORGANISM(S): Homo sapiens

PROVIDER: GSE55036 | GEO | 2015/06/05

SECONDARY ACCESSION(S): PRJNA238310

REPOSITORIES: GEO

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