Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Antonio Parrado
PROVIDER: E-GEOD-55288 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
PloS one 20141003 10
Interleukin 4 (IL-4), an essential mediator of B cell development, plays a role in survival of chronic lymphocytic leukemia (CLL) cells. To obtain new insights into the function of the IL-4 pathway in CLL, we analyzed the gene expression response to IL-4 in CLL and in normal B cells (NBC) by oligonucleotide microarrays, resulting in the identification of 232 non-redundant entities in CLL and 146 in NBC (95 common, 283 altogether), of which 189 were well-defined genes in CLL and 123 in NBC (83 co ...[more]