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Loss and dysfunction of Vdelta2+ gammadelta-low T cells is associated with clinical tolerance to malaria

ABSTRACT: Gammadelta T cells from Ugandan children were tested for their responsiveness to stimulation with malaria parasites. Independent PBMC samples from children were incubated with Plasmodium falciparum-infected red blood cells for 6 h post-treatment, and Vdelta2+ gammadelta T cells were double sorted by FACS directly into an RNA lysis buffer. RNA was isolated, amplified using 2 rounds of linear amplification, and hybridized to Agilent Human 8x60k microarrays as a single color experiment.

ORGANISM(S): Homo sapiens

SUBMITTER: Charlie Kim

PROVIDER: E-GEOD-55843 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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