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ETV5 transcription program links BDNF and promotion of EMT at invasive front of endometrial carcinomas.

ABSTRACT: We have characterized the transcriptional program regulated by ETV5 at the invasive front of endometrial carcinomas, by comparing it with non-invasive areas of the same tumor samples. In total 12 samples; 6 superficial (non-invasive) tumor areas and the corresponding invasive tumor zones.

ORGANISM(S): Homo sapiens

SUBMITTER: Miguel Abal

PROVIDER: E-GEOD-57870 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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ETV5 transcription program links BDNF and promotion of EMT at invasive front of endometrial carcinomas.

Alonso-Alconada Lorena L Eritja Nuria N Muinelo-Romay Laura L Barbazan Jorge J Lopez-Lopez Rafael R Matias-Guiu Xavier X Gil-Moreno Antonio A Dolcet Xavier X Abal Miguel M

Carcinogenesis 20140918 12

Myometrial infiltration represents a main clinical determinant of endometrial carcinomas (EC) presenting as aggressive high-grade deeply invasive neoplasms, substantially associated with risk of recurrence and death. The up-regulation of ETV5 transcription factor linked to the promotion of epithelial to mesenchymal transition is considered as a basic mechanism underlying the initial steps of EC invasion. In this work, we aimed to investigate the transcription program of tumor invasion regulated ...[more]

PMID: 25233929

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ETV5 transcription program links BDNF and promotion of EMT at invasive front of endometrial carcinomas.

Project description:We have characterized the transcriptional program regulated by ETV5 at the invasive front of endometrial carcinomas, by comparing it with non-invasive areas of the same tumor samples.

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Expression data from cells located at the invasive front and in the tumor mass of mouse cervical squamous cell carcinomas

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Genome wide analysis of bivalent domains in two HUES cell lines

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Deregulated MicroRNAs in Cancer-Associated Fibroblasts from Front Tumor Tissues of Lung Adenocarcinoma as Potential Predictors of Tumor Promotion

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Whole transcriptome assay of human urinary bladder cancer tumor samples from the central part and invasive front of individual tumors

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Genome-wide DNA methylation analysis on testicular embryonal carcinoma

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| PRJNA718540 | ENA