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Identification of IL-23 target genes in intestinal CD4+ T cells

ABSTRACT: IL-23 negatively regulates St2 and Gata3 expression in intestinal CD4+ T cells Colitis was induced by co-transfer of WT and Il23r-/- naïve CD4 T cells into Rag1-/- recipients. Upon development of clinical signs of inflammation WT and Il23r-/- CD4+ T cells were sort-purified from the colon lamina propria on the basis of congenic markers. Total RNA was extracted immediately after the sort without further manipulation.

ORGANISM(S): Mus musculus

SUBMITTER: Chris Schiering

PROVIDER: E-GEOD-58147 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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