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RNA sequencing of mouse littermate wild-type and Shh null E10.5 forelimbs [Illumina]

ABSTRACT: We wanted to identify differentially expressed genes in wild-type and Shh null E10.5 mouse forelimbs Used two wild-type technical replicates and two Shh null technical replicates UT-Genome and Analysis Facility

ORGANISM(S): Mus musculus

SUBMITTER: jordan lewandowski

PROVIDER: E-GEOD-58645 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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RNA sequencing of mouse littermate wild-type and Shh null E10.5 forelimbs [Illumina]

Project description:We wanted to identify differentially expressed genes in wild-type and Shh null E10.5 mouse forelimbs

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RNA sequencing of cultured mouse wild-type E10.25 forelimbs in control or cyclopmaine containing media [SOLiD]

Project description:We wanted to identify differentially expressed genes in wild-type forelimbs and forelimbs briefly exposed to Shh signaling. E10.25 forelimbs were cultured in control media and media containing cyclopmaine (inhibits the Hedgehog pathway) Generated two wild-type (control) and two cyclopmaine biological replicates for RNA-seq UT-Genome and Analysis Facility

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Expression data from E11.5 mouse embryonic forelimbs - various mutant conditions or dissected limb domains

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RNA-seq experiment of developing mouse forelimbs, comparing Bcl9/9l mutant with control littermates.

Project description:Forelimbs were manually dissected from three individual Bcl9/9l-deltaHD1/deltaHD2 mutants and three control littermates, at 10.5 days post coitum. BCL9 and BCL9L are paralogous beta-catenin cofactors involved in the transcriptional machinery of Wnt target genes.

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H3K27ac in WT and Shh-/-, and Shh-/- Gli3-/- E10.5 limb buds

Project description:H3K27ac in WT and Shh-/-, and Shh-/- Gli3-/- E10.5 limb buds

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H3K27ac in WT and Shh-/-, and Shh-/-;Gli3-/- E10.5 limb buds

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